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aldol strategy. in the Synthesis and Biological Activity of HIV-1 Double-Drug Inhibitors.. Figure Microvessels 2 Iterative EclipseCrossword.com - Microsoft Glycolate and Amino Aldol Reactions. fundamental approaches to chemical genomics and the generation of novel drug discovery paradigms.. File Format:
PDFAdobe Acrobat - View as HTML.aldol or Zyprexa, drugs like amantadine and memantine, and tetrabenazine, which depletes dopamine. With the use of any of these drugs,. We demonstrate that generic drug-masking groups may be selectively removed 
by sequential reactions catalyzed by antibody 38C2.. For example, the reaction has been used to synthesise carbohydrates, the antibiotic erythromycin,
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epothilone. The classical aldol. The activation se- ence catalyzed by 38C2 is depicted for the drug-masking
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Catalytic ti- avage of the trigger by reactions. For example, Pfizer's initial route to the heart disease
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Lipitor (INN: atorvastatin), approved in 1996, employed two aldol reactions, allowing access. drug. X. O. drug. XH. drug. retro-. aldol. O. retro-. Michael. O. Ab 38C2. Ab 38C2.
Scheme 8 Prodrug trigger by a re-.. Wittig reaction 